E2F transcription factors are differentially expressed in murine gametes and early embryos

نویسندگان

  • Antonella Palena
  • Rosamaria Mangiacasale
  • Anna Rosa Magnano
  • Laura Barberi
  • Roberto Giordano
  • Corrado Spadafora
  • Patrizia Lavia
چکیده

We have examined the murine genes encoding transcription factors E2F1, -3, -5 and -6 in gametes and early embryos. All genes are expressed as maternal transcripts and all are efficiently transcribed after the blastocyst stage. Between those two stages, each E2F mRNA is transcribed with a distinctive and unique pattern. E2F proteins are also differentially expressed and compartmentalized in pre-implantation embryos.

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عنوان ژورنال:
  • Mechanisms of Development

دوره 97  شماره 

صفحات  -

تاریخ انتشار 2000